A List of Recent Talk Show’s Very First Guests

Jimmy Kimmel, Jimmy Kimmel Live (2003-present): George Clooney

Ellen DeGeneres, The Ellen DeGeneres Show (2003-present): Jennifer Aniston

Jimmy Fallon, Late Night (2009): Robert DeNiro

  • Conan O’Brien, The Tonight Show (2009-2010): Will Ferrell 
  • Jay Leno, The Jay Leno Show (2009-2010): Jerry Seinfeld
  • Jay Leno, The Tonight Show (2010-present): Lindsey Vonn
  • Nate Berkus, The Nate Berkus Show (2010-2012): Dolly Parton
  • Conan O’Brien, Conan (2010-present): Arlene Wagner [curator, Leavenworth Nutcracker Museum]
  • Anderson Cooper, Anderson (2011-present): the family of Amy Winehouse
  • Bethenny Frankel, Bethenny (2012-present): Vanessa L. Williams
  • Jeff Probst, The Jeff Probst Show (2012-present): Kelly Pozzoli, schoolteacher with cervical cancer
  • Katie Couric, Katie (2012-present): Jessica Simpson