Trayf Chic! Pig-Derived ‘Evolence’ Freshens City Faces

Over the past few years, age-conscious Manhattanites have filled their faces with all kinds of crazy stuff, from Botox to

Over the past few years, age-conscious Manhattanites have filled their faces with all kinds of crazy stuff, from Botox to hyaluronic acids to fat from their own saddlebags. But recently, Jennifer, a slender 50-year-old who works on Wall Street, decided to plump up her cheeks with a new collagen called Evolence, made from pig tendons, that she had seen advertised on television. “They mentioned that Demi Moore supposedly used it for laugh lines,” she said. “They intimated. And that kind of did it for me.”

Jennifer was untroubled by the barnyard origins of Evolence, which arrived on the market in September 2008 but has yet to become a buzzword on the society circuit. “I heard in the media that it was derived from the pig and it sounded rather gross to me, but then they elaborated that we have similar tissue,” she said breezily.

And so on Monday, March 2, Jennifer arrived at the Park Avenue office of Darrick Antell, a plastic surgeon. Dr. Antell’s nurse wiped the makeup from the patient’s cheeks and applied a topical anesthetic; the doctor himself then injected a single syringe of whitish substance into her cheeks via a tiny 30-gauge needle. The entire procedure took 15 minutes and cost $700. Jennifer rode the subway immediately back to work afterward.

“I love it!” she enthused, calling from her office several days later. “I’m getting looks. ‘Oh, your skin looks great.’ I think it’s because the cheekbones are a little more defined. It’s kind of subtle.” There has been no bruising and no swelling—common, if typically short-lived, side effects of hyaluronic acid injections—just a minor, lingering pain to the touch. She even went back for another syringe the next day. “I just thought it looked so pretty,” she said.



In the 1980s, we got ourselves shot full of bovine collagen (which required an allergy test several weeks beforehand, never desirable when one is seeking an instant pick-me-up). In the ’90s, we began freezing our faces with a derivative of the botulism toxin. In 2003 came Restylane, a breakthrough hyaluronic acid (or H.A., as it’s known in the trade) derived from bacteria. Nowadays many New York doctors also offer Radiesse, a filler made of synthetic liquid bone, and Sculptra, which was invented to treat the hollow cheeks of H.I.V. patients. 

But … pig fat? Oy vay!

“It’s a huge breakthrough,” argued Dr. David Goldberg, a dermatology professor at Mt. Sinai School of Medicine, who will soon publish a study on the use of Evolence in the eyelids; he estimates he’s used it on 200 or so patients already. “There’s nothing wrong with the H.A.’s, but the negatives of H.A.’s historically have been that there can be a fair amount of swelling, which you don’t get from any collagen, including Evolence.”

“It’s easier in some cases to hide from the husband,” allowed Dr. Howard Sobel, a Park Avenue cosmetic dermatologist, in an email.

Carol R., 52, an Upper East Sider who has previously been injected with Restylane, Radiesse, Juvederm and longer-lasting silicon, tried Evolence from Dr. Sobel’s needle for the first time two months ago. “I usually bruise down on my chin no matter what they inject,” she said. “It gets blue, and then it gets purple. It’s not very attractive. You look like either you got punched in the face or you did something. Every woman knows you did something.”

But with Evolence, Carol exulted, “I didn’t swell at all!” She went out to dinner with two other couples the night of her injection. And it didn’t trouble her in the slightest that what was in her face might also have been offered on the menu. “I had [bovine] collagen for years,” she said. “I guess if you could eat bacon, you can put it in your face! And I like bacon!”

Doctors similarly scoff at the notion that New York women might be wary of using pig fat to achieve a baby face. “Oh, come on, when it comes to beauty?” said Dr. Francesca Fusco, a much-loved dermatologist who shares offices with Dr. Patricia Wexler. “In all the years I’ve practiced, nobody’s ever said, ‘I’m a vegetarian, so I don’t want the bovine-based collagen.’” Indeed, perhaps our fetishization of the greenmarket has made us more inclined to pork up, facially speaking. “It’s like we have farm-fresh faces!” Dr. Fusco giggled.

“A lot of people would rather have a natural substance derived from a pig than a substance made in some laboratory,” Dr. Goldberg said (H.A.s are cross-linked by chemicals; the creation of Evolence entails a patented technology involving sugar, sort of like a closely guarded barbecue-rub recipe).

Perhaps Evolence’s most surprising characteristic, however, is that it is made in … Israel, by a company called ColBar Life Sciences, which was purchased by Johnson & Johnson, the squeaky-clean American company widely associated with plump baby faces, in 2006.

“We think we have a game-changer on our hands,” declared Monica Neufang, a Johnson & Johnson spokeswoman for  Evolence, just after returning from the annual meeting of the American Academy of Dermatology in San Francisco, which she called the new brand’s “coming out.” (They had wooed dermatologists with live demonstrations and dinners).

Ms. Neufang said that the product had been approved by at least one rabbinical council but that religious patients should consult their rabbis for guidance “We do not have rabbis on staff,” she said. But: “By the time you purify the product, the collagen that results is virtually identical to human collagen.”

She admitted that her company has thus far been rolling out its find rather stealthily. “Our product injects very differently than H.A.’s, and since that is the lion’s share of the market, we wanted to make sure we have a robust training program in place for physicians, so we’ve really been focusing on that for the first six months,” she said. But in the next month or so, get ready to see Evolence everywhere, as the brand targets consumers more directly.

Trayf Chic! Pig-Derived ‘Evolence’ Freshens City Faces