Catherine Zeta-Jones, who’s enjoying a mini-comeback with a slate of upcoming films including the musical Rock of Ages, has reportedly been cast as a doctor in Side Effects, an upcoming Steven Soderbergh thriller wherein Blake Lively takes pharmaceuticals to mute the effects of her depression. Ms. Zeta-Jones previously appeared in Mr. Soderbergh’s Traffic and Ocean’s Twelve, and in an interesting congruence, bravely went public with her own bipolar disorder last year.